Israeli Institute Finds New Effective Cancer Treatment Using Immune Cells
Winning on the battlefield takes a combination of determined soldiers and precise intelligence, but when it comes to the battle against cancer, the immune system’s fighters – the T cells – quickly lose their ability to kill and become exhausted, while the intelligence-providing dendritic cells (DCs) are scarce.
Now, researchers at the Weizmann Institute of Science in Rehovot have discovered a new kind of immunotherapy based on intercommunication among different immune cells. They say this technique could pave the way for innovative treatments of cancer and autoimmune diseases.
The effectiveness of this new treatment was tested in several mouse models of cancer, including aggressive breast, lung, and skin cancers. Treatment with the new antibody, as compared to the existing treatment, significantly reduced the growth rate of skin and lung cancers.
In contrast, breast tumors that did not respond to the existing treatment also failed to respond to the new antibody. Researchers believe this is because of the very small number of active dendritic cells around these tumors. Therefore, they tried combining their new antibody with an existing treatment that enhances the activity of dendritic cells around the growth.
This combined treatment was found to be more effective than the existing options. It proved that even in cancers that had not responded to immunotherapy until now, the synergy between T cells and active dendritic cells creates a powerful immune response against the tumor. (JPost / VFI News)
“God, we thank You for gifting us brilliant scientists who research and develop groundbreaking technologies to heal cancer. We are extremely grateful for them, and we hope that this recent medical discovery will pave the way for the quick and painless elimination of all types of cancer and autoimmune diseases.”
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